# Update FHIR r4 medication knowledge

Endpoint: PUT /site/{siteId}/fhir/medication-knowledge/{id}
Version: 1.0
Security: bearer, bearer

## Path parameters:

  - `siteId` (string, required)
    Site identifier

  - `id` (string, required)
    ID of the MedicationKnowledge to update

## Request fields (application/json):

  - `resourceType` (any, required)
    This is a MedicationKnowledge resource
    Enum: "MedicationKnowledge"

  - `id` (string)
    Any combination of letters, numerals, "-" and ".", with a length limit of 64 characters.  (This might be an integer, an unprefixed OID, UUID or any other identifier pattern that meets these constraints.)  Ids are case-insensitive.
    Example: "example-id"

  - `meta` (object)
    The metadata about a resource. This is content in the resource that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

  - `meta.id` (string)
    An extension object type #string.
    Example: "example-string"

  - `meta.extension` (array)
    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

  - `meta.versionId` (object)
    An extension object type #id.

  - `meta._versionId` (object)
    An extension object type #Element.

  - `meta.lastUpdated` (object)
    An extension object type #instant.

  - `meta._lastUpdated` (object)
    An extension object type #Element.

  - `meta.source` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `meta._source` (object)
    An extension object type #Element.

  - `meta.profile` (array)
    A list of profiles (references to [[[StructureDefinition]]] resources) that this resource claims to conform to. The URL is a reference to [[[StructureDefinition.url]]].
    Example: ["http://example.org/Profile"]

  - `meta.security` (array)
    Security labels applied to this resource. These tags connect specific resources to the overall security policy and infrastructure.

  - `meta.tag` (array)
    Tags applied to this resource. Tags are intended to be used to identify and relate resources to process and workflow, and applications are not required to consider the tags when interpreting the meaning of a resource.

  - `implicitRules` (string)
    String of characters used to identify a name or a resource
    Example: "https://example.org/resource"

  - `_implicitRules` (object)
    Base definition for all elements in a resource.

  - `language` (string)
    A string which has at least one character and no leading or trailing whitespace and where there is no whitespace other than single spaces in the contents
    Example: "sample-code"

  - `_language` (object)
    Base definition for all elements in a resource.

  - `text` (object)
    A human-readable summary of the resource conveying the essential clinical and business information for the resource.

  - `text.status` (any)
    The status of the narrative - whether it's entirely generated (from just the defined data or the extensions too), or whether a human authored it and it may contain additional data.
    Enum: "generated", "extensions", "additional", "empty"

  - `text._status` (object)
    An extension object type #Element.

  - `text.div` (string, required)
    An extension object type #xhtml.
    Example: "<div>Example</div>"

  - `contained` (array)
    These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.
    Example: [{"resourceType":"Organization","id":"org4","name":"Pfizer Laboratories Div Pfizer Inc"}]

  - `extension` (array)
    May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

  - `extension.url` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `extension._url` (object)
    An extension object type #Element.

  - `extension.valueBase64Binary` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "U2FtcGxl"

  - `extension._valueBase64Binary` (object)
    An extension object type #Element.

  - `extension.valueBoolean` (boolean)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: true

  - `extension._valueBoolean` (object)
    An extension object type #Element.

  - `extension.valueCanonical` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "http://example.org/Profile"

  - `extension._valueCanonical` (object)
    An extension object type #Element.

  - `extension.valueCode` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "sample-code"

  - `extension._valueCode` (object)
    An extension object type #Element.

  - `extension.valueDate` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01"

  - `extension._valueDate` (object)
    An extension object type #Element.

  - `extension.valueDateTime` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01T00:00:00Z"

  - `extension._valueDateTime` (object)
    An extension object type #Element.

  - `extension.valueDecimal` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1.23

  - `extension._valueDecimal` (object)
    An extension object type #Element.

  - `extension.valueId` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "example-id"

  - `extension._valueId` (object)
    An extension object type #Element.

  - `extension.valueInstant` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01T00:00:00Z"

  - `extension._valueInstant` (object)
    An extension object type #Element.

  - `extension.valueInteger` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1

  - `extension._valueInteger` (object)
    An extension object type #Element.

  - `extension.valueMarkdown` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "Sample markdown text"

  - `extension._valueMarkdown` (object)
    An extension object type #Element.

  - `extension.valueOid` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "urn:oid:1.2.3.4.5"

  - `extension._valueOid` (object)
    An extension object type #Element.

  - `extension.valuePositiveInt` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1

  - `extension._valuePositiveInt` (object)
    An extension object type #Element.

  - `extension.valueString` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "example-string"

  - `extension._valueString` (object)
    An extension object type #Element.

  - `extension.valueTime` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "12:00:00"

  - `extension._valueTime` (object)
    An extension object type #Element.

  - `extension.valueUnsignedInt` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).

  - `extension._valueUnsignedInt` (object)
    An extension object type #Element.

  - `extension.valueUri` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "https://example.org/resource"

  - `extension._valueUri` (object)
    An extension object type #Element.

  - `extension.valueUrl` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "https://example.org"

  - `extension._valueUrl` (object)
    An extension object type #Element.

  - `extension.valueUuid` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "urn:uuid:123e4567-e89b-12d3-a456-426614174000"

  - `extension._valueUuid` (object)
    An extension object type #Element.

  - `extension.valueAddress` (object)
    An extension object type #Address.

  - `extension.valueAge` (object)
    An extension object type #Age.

  - `extension.valueAnnotation` (object)
    An extension object type #Annotation.

  - `extension.valueAttachment` (object)
    An extension object type #Attachment.

  - `extension.valueCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `extension.valueCoding` (object)
    An extension object type #Coding.

  - `extension.valueContactPoint` (object)
    An extension object type #ContactPoint.

  - `extension.valueCount` (object)
    An extension object type #Count.

  - `extension.valueDistance` (object)
    An extension object type #Distance.

  - `extension.valueDuration` (object)
    An extension object type #Duration.

  - `extension.valueHumanName` (object)
    An extension object type #HumanName.

  - `extension.valueIdentifier` (object)
    An extension object type #Identifier.

  - `extension.valueMoney` (object)
    An extension object type #Money.

  - `extension.valuePeriod` (object)
    An extension object type #Period.

  - `extension.valueQuantity` (object)
    An extension object type #Quantity.

  - `extension.valueRange` (object)
    An extension object type #Range.

  - `extension.valueRatio` (object)
    An extension object type #Ratio.

  - `extension.valueReference` (object)
    An extension object type #Reference.

  - `extension.valueSampledData` (object)
    An extension object type #SampledData.

  - `extension.valueSignature` (object)
    An extension object type #Signature.

  - `extension.valueTiming` (object)
    An extension object type #Timing.

  - `extension.valueContactDetail` (object)
    An extension object type #ContactDetail.

  - `extension.valueContributor` (object)
    An extension object type #Contributor.

  - `extension.valueDataRequirement` (object)
    An extension object type #DataRequirement.

  - `extension.valueExpression` (object)
    An extension object type #Expression.

  - `extension.valueParameterDefinition` (object)
    An extension object type #ParameterDefinition.

  - `extension.valueRelatedArtifact` (object)
    An extension object type #RelatedArtifact.

  - `extension.valueTriggerDefinition` (object)
    An extension object type #TriggerDefinition.

  - `extension.valueUsageContext` (object)
    An extension object type #UsageContext.

  - `extension.valueDosage` (object)
    An extension object type #Dosage.

  - `extension.valueMeta` (object)
    An extension object type #Meta.

  - `modifierExtension` (array)
    May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

  - `code` (object)
    A concept that may be defined by a formal reference to a terminology or ontology or may be provided by text.

  - `code.coding` (array)
    A reference to a code defined by a terminology system.

  - `code.text` (string)
    An extension object type #string.
    Example: "example-string"

  - `code._text` (object)
    An extension object type #Element.

  - `status` (string)
    A string which has at least one character and no leading or trailing whitespace and where there is no whitespace other than single spaces in the contents
    Example: "sample-code"

  - `_status` (object)
    Base definition for all elements in a resource.

  - `manufacturer` (object)
    A reference from one resource to another.

  - `manufacturer.reference` (string)
    An extension object type #string.
    Example: "example-string"

  - `manufacturer._reference` (object)
    An extension object type #Element.

  - `manufacturer.type` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `manufacturer._type` (object)
    An extension object type #Element.

  - `manufacturer.identifier` (object)
    An extension object type #Identifier.

  - `manufacturer.display` (string)
    An extension object type #string.
    Example: "example-string"

  - `manufacturer._display` (object)
    An extension object type #Element.

  - `doseForm` (object)
    A concept that may be defined by a formal reference to a terminology or ontology or may be provided by text.

  - `amount` (object)
    A measured amount (or an amount that can potentially be measured). Note that measured amounts include amounts that are not precisely quantified, including amounts involving arbitrary units and floating currencies.

  - `amount.value` (number)
    An extension object type #decimal.
    Example: 1.23

  - `amount._value` (object)
    An extension object type #Element.

  - `amount.comparator` (any)
    How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is "<" , then the real value is < stated value.
    Enum: "<", "<=", ">=", ">"

  - `amount._comparator` (object)
    An extension object type #Element.

  - `amount.unit` (string)
    An extension object type #string.
    Example: "example-string"

  - `amount._unit` (object)
    An extension object type #Element.

  - `amount.system` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `amount._system` (object)
    An extension object type #Element.

  - `amount.code` (string)
    An extension object type #code.
    Example: "sample-code"

  - `amount._code` (object)
    An extension object type #Element.

  - `synonym` (array)
    Additional names for a medication, for example, the name(s) given to a medication in different countries.  For example, acetaminophen and paracetamol or salbutamol and albuterol.
    Example: ["Vancomycin Hydrochloride (VANCOMYCIN HYDROCHLORIDE)"]

  - `_synonym` (array)
    Extensions for synonym

  - `relatedMedicationKnowledge` (array)
    Associated or related knowledge about a medication.

  - `relatedMedicationKnowledge.modifierExtension` (array)
    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

  - `relatedMedicationKnowledge.type` (object, required)
    An extension object type #CodeableConcept.

  - `relatedMedicationKnowledge.reference` (array, required)
    Associated documentation about the associated medication knowledge.

  - `associatedMedication` (array)
    Associated or related medications.  For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor).

  - `productType` (array)
    Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).

  - `monograph` (array)
    Associated documentation about the medication.

  - `monograph.source` (object)
    An extension object type #Reference.

  - `ingredient` (array)
    Identifies a particular constituent of interest in the product.

  - `ingredient.itemCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `ingredient.itemReference` (object)
    An extension object type #Reference.

  - `ingredient.isActive` (boolean)
    An extension object type #boolean.
    Example: true

  - `ingredient._isActive` (object)
    An extension object type #Element.

  - `ingredient.strength` (object)
    An extension object type #Ratio.

  - `preparationInstruction` (string)
    A string that may contain Github Flavored Markdown syntax for optional processing by a mark down presentation engine
    Example: "Sample markdown text"

  - `_preparationInstruction` (object)
    Base definition for all elements in a resource.

  - `intendedRoute` (array)
    The intended or approved route of administration.

  - `cost` (array)
    The price of the medication.

  - `cost.source` (string)
    An extension object type #string.
    Example: "example-string"

  - `cost.cost` (object, required)
    An extension object type #Money.

  - `monitoringProgram` (array)
    The program under which the medication is reviewed.

  - `monitoringProgram.name` (string)
    An extension object type #string.
    Example: "example-string"

  - `monitoringProgram._name` (object)
    An extension object type #Element.

  - `administrationGuidelines` (array)
    Guidelines for the administration of the medication.

  - `administrationGuidelines.dosage` (array)
    Dosage for the medication for the specific guidelines.

  - `administrationGuidelines.indicationCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `administrationGuidelines.indicationReference` (object)
    An extension object type #Reference.

  - `administrationGuidelines.patientCharacteristics` (array)
    Characteristics of the patient that are relevant to the administration guidelines (for example, height, weight, gender, etc.).

  - `medicineClassification` (array)
    Categorization of the medication within a formulary or classification system.

  - `medicineClassification.classification` (array)
    Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).

  - `packaging` (object)
    Information about a medication that is used to support knowledge.

  - `packaging.quantity` (object)
    An extension object type #Quantity.

  - `drugCharacteristic` (array)
    Specifies descriptive properties of the medicine, such as color, shape, imprints, etc.

  - `drugCharacteristic.valueString` (string)
    Description of the characteristic.
    Example: "example-string"

  - `drugCharacteristic.valueBase64Binary` (string)
    Description of the characteristic.
    Example: "U2FtcGxl"

  - `contraindication` (array)
    Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).

  - `regulatory` (array)
    Regulatory information about a medication.

  - `regulatory.regulatoryAuthority` (object, required)
    An extension object type #Reference.

  - `regulatory.substitution` (array)
    Specifies if changes are allowed when dispensing a medication from a regulatory perspective.

  - `regulatory.schedule` (array)
    Specifies the schedule of a medication in jurisdiction.

  - `regulatory.maxDispense` (object)
    An extension object type #MedicationKnowledge_MaxDispense.

  - `kinetics` (array)
    The time course of drug absorption, distribution, metabolism and excretion of a medication from the body.

  - `kinetics.areaUnderCurve` (array)
    The drug concentration measured at certain discrete points in time.

  - `kinetics.lethalDose50` (array)
    The median lethal dose of a drug.

  - `kinetics.halfLifePeriod` (object)
    An extension object type #Duration.

## Response 200 fields (application/json):

  - `resourceType` (any, required)
    This is a MedicationKnowledge resource
    Enum: "MedicationKnowledge"

  - `id` (string)
    Any combination of letters, numerals, "-" and ".", with a length limit of 64 characters.  (This might be an integer, an unprefixed OID, UUID or any other identifier pattern that meets these constraints.)  Ids are case-insensitive.
    Example: "example-id"

  - `meta` (object)
    The metadata about a resource. This is content in the resource that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

  - `meta.id` (string)
    An extension object type #string.
    Example: "example-string"

  - `meta.extension` (array)
    May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

  - `meta.versionId` (object)
    An extension object type #id.

  - `meta._versionId` (object)
    An extension object type #Element.

  - `meta.lastUpdated` (object)
    An extension object type #instant.

  - `meta._lastUpdated` (object)
    An extension object type #Element.

  - `meta.source` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `meta._source` (object)
    An extension object type #Element.

  - `meta.profile` (array)
    A list of profiles (references to [[[StructureDefinition]]] resources) that this resource claims to conform to. The URL is a reference to [[[StructureDefinition.url]]].
    Example: ["http://example.org/Profile"]

  - `meta.security` (array)
    Security labels applied to this resource. These tags connect specific resources to the overall security policy and infrastructure.

  - `meta.tag` (array)
    Tags applied to this resource. Tags are intended to be used to identify and relate resources to process and workflow, and applications are not required to consider the tags when interpreting the meaning of a resource.

  - `implicitRules` (string)
    String of characters used to identify a name or a resource
    Example: "https://example.org/resource"

  - `_implicitRules` (object)
    Base definition for all elements in a resource.

  - `language` (string)
    A string which has at least one character and no leading or trailing whitespace and where there is no whitespace other than single spaces in the contents
    Example: "sample-code"

  - `_language` (object)
    Base definition for all elements in a resource.

  - `text` (object)
    A human-readable summary of the resource conveying the essential clinical and business information for the resource.

  - `text.status` (any)
    The status of the narrative - whether it's entirely generated (from just the defined data or the extensions too), or whether a human authored it and it may contain additional data.
    Enum: "generated", "extensions", "additional", "empty"

  - `text._status` (object)
    An extension object type #Element.

  - `text.div` (string, required)
    An extension object type #xhtml.
    Example: "<div>Example</div>"

  - `contained` (array)
    These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope.
    Example: [{"resourceType":"Organization","id":"org4","name":"Pfizer Laboratories Div Pfizer Inc"}]

  - `extension` (array)
    May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

  - `extension.url` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `extension._url` (object)
    An extension object type #Element.

  - `extension.valueBase64Binary` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "U2FtcGxl"

  - `extension._valueBase64Binary` (object)
    An extension object type #Element.

  - `extension.valueBoolean` (boolean)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: true

  - `extension._valueBoolean` (object)
    An extension object type #Element.

  - `extension.valueCanonical` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "http://example.org/Profile"

  - `extension._valueCanonical` (object)
    An extension object type #Element.

  - `extension.valueCode` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "sample-code"

  - `extension._valueCode` (object)
    An extension object type #Element.

  - `extension.valueDate` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01"

  - `extension._valueDate` (object)
    An extension object type #Element.

  - `extension.valueDateTime` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01T00:00:00Z"

  - `extension._valueDateTime` (object)
    An extension object type #Element.

  - `extension.valueDecimal` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1.23

  - `extension._valueDecimal` (object)
    An extension object type #Element.

  - `extension.valueId` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "example-id"

  - `extension._valueId` (object)
    An extension object type #Element.

  - `extension.valueInstant` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "2024-01-01T00:00:00Z"

  - `extension._valueInstant` (object)
    An extension object type #Element.

  - `extension.valueInteger` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1

  - `extension._valueInteger` (object)
    An extension object type #Element.

  - `extension.valueMarkdown` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "Sample markdown text"

  - `extension._valueMarkdown` (object)
    An extension object type #Element.

  - `extension.valueOid` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "urn:oid:1.2.3.4.5"

  - `extension._valueOid` (object)
    An extension object type #Element.

  - `extension.valuePositiveInt` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: 1

  - `extension._valuePositiveInt` (object)
    An extension object type #Element.

  - `extension.valueString` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "example-string"

  - `extension._valueString` (object)
    An extension object type #Element.

  - `extension.valueTime` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "12:00:00"

  - `extension._valueTime` (object)
    An extension object type #Element.

  - `extension.valueUnsignedInt` (number)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).

  - `extension._valueUnsignedInt` (object)
    An extension object type #Element.

  - `extension.valueUri` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "https://example.org/resource"

  - `extension._valueUri` (object)
    An extension object type #Element.

  - `extension.valueUrl` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "https://example.org"

  - `extension._valueUrl` (object)
    An extension object type #Element.

  - `extension.valueUuid` (string)
    Value of extension - must be one of a constrained set of the data types (see [Extensibility](https://hl7.org/fhir/extensibility.html) for a list).
    Example: "urn:uuid:123e4567-e89b-12d3-a456-426614174000"

  - `extension._valueUuid` (object)
    An extension object type #Element.

  - `extension.valueAddress` (object)
    An extension object type #Address.

  - `extension.valueAge` (object)
    An extension object type #Age.

  - `extension.valueAnnotation` (object)
    An extension object type #Annotation.

  - `extension.valueAttachment` (object)
    An extension object type #Attachment.

  - `extension.valueCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `extension.valueCoding` (object)
    An extension object type #Coding.

  - `extension.valueContactPoint` (object)
    An extension object type #ContactPoint.

  - `extension.valueCount` (object)
    An extension object type #Count.

  - `extension.valueDistance` (object)
    An extension object type #Distance.

  - `extension.valueDuration` (object)
    An extension object type #Duration.

  - `extension.valueHumanName` (object)
    An extension object type #HumanName.

  - `extension.valueIdentifier` (object)
    An extension object type #Identifier.

  - `extension.valueMoney` (object)
    An extension object type #Money.

  - `extension.valuePeriod` (object)
    An extension object type #Period.

  - `extension.valueQuantity` (object)
    An extension object type #Quantity.

  - `extension.valueRange` (object)
    An extension object type #Range.

  - `extension.valueRatio` (object)
    An extension object type #Ratio.

  - `extension.valueReference` (object)
    An extension object type #Reference.

  - `extension.valueSampledData` (object)
    An extension object type #SampledData.

  - `extension.valueSignature` (object)
    An extension object type #Signature.

  - `extension.valueTiming` (object)
    An extension object type #Timing.

  - `extension.valueContactDetail` (object)
    An extension object type #ContactDetail.

  - `extension.valueContributor` (object)
    An extension object type #Contributor.

  - `extension.valueDataRequirement` (object)
    An extension object type #DataRequirement.

  - `extension.valueExpression` (object)
    An extension object type #Expression.

  - `extension.valueParameterDefinition` (object)
    An extension object type #ParameterDefinition.

  - `extension.valueRelatedArtifact` (object)
    An extension object type #RelatedArtifact.

  - `extension.valueTriggerDefinition` (object)
    An extension object type #TriggerDefinition.

  - `extension.valueUsageContext` (object)
    An extension object type #UsageContext.

  - `extension.valueDosage` (object)
    An extension object type #Dosage.

  - `extension.valueMeta` (object)
    An extension object type #Meta.

  - `modifierExtension` (array)
    May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

  - `code` (object)
    A concept that may be defined by a formal reference to a terminology or ontology or may be provided by text.

  - `code.coding` (array)
    A reference to a code defined by a terminology system.

  - `code.text` (string)
    An extension object type #string.
    Example: "example-string"

  - `code._text` (object)
    An extension object type #Element.

  - `status` (string)
    A string which has at least one character and no leading or trailing whitespace and where there is no whitespace other than single spaces in the contents
    Example: "sample-code"

  - `_status` (object)
    Base definition for all elements in a resource.

  - `manufacturer` (object)
    A reference from one resource to another.

  - `manufacturer.reference` (string)
    An extension object type #string.
    Example: "example-string"

  - `manufacturer._reference` (object)
    An extension object type #Element.

  - `manufacturer.type` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `manufacturer._type` (object)
    An extension object type #Element.

  - `manufacturer.identifier` (object)
    An extension object type #Identifier.

  - `manufacturer.display` (string)
    An extension object type #string.
    Example: "example-string"

  - `manufacturer._display` (object)
    An extension object type #Element.

  - `doseForm` (object)
    A concept that may be defined by a formal reference to a terminology or ontology or may be provided by text.

  - `amount` (object)
    A measured amount (or an amount that can potentially be measured). Note that measured amounts include amounts that are not precisely quantified, including amounts involving arbitrary units and floating currencies.

  - `amount.value` (number)
    An extension object type #decimal.
    Example: 1.23

  - `amount._value` (object)
    An extension object type #Element.

  - `amount.comparator` (any)
    How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is "<" , then the real value is < stated value.
    Enum: "<", "<=", ">=", ">"

  - `amount._comparator` (object)
    An extension object type #Element.

  - `amount.unit` (string)
    An extension object type #string.
    Example: "example-string"

  - `amount._unit` (object)
    An extension object type #Element.

  - `amount.system` (string)
    An extension object type #uri.
    Example: "https://example.org/resource"

  - `amount._system` (object)
    An extension object type #Element.

  - `amount.code` (string)
    An extension object type #code.
    Example: "sample-code"

  - `amount._code` (object)
    An extension object type #Element.

  - `synonym` (array)
    Additional names for a medication, for example, the name(s) given to a medication in different countries.  For example, acetaminophen and paracetamol or salbutamol and albuterol.
    Example: ["Vancomycin Hydrochloride (VANCOMYCIN HYDROCHLORIDE)"]

  - `_synonym` (array)
    Extensions for synonym

  - `relatedMedicationKnowledge` (array)
    Associated or related knowledge about a medication.

  - `relatedMedicationKnowledge.modifierExtension` (array)
    May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

  - `relatedMedicationKnowledge.type` (object, required)
    An extension object type #CodeableConcept.

  - `relatedMedicationKnowledge.reference` (array, required)
    Associated documentation about the associated medication knowledge.

  - `associatedMedication` (array)
    Associated or related medications.  For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor).

  - `productType` (array)
    Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).

  - `monograph` (array)
    Associated documentation about the medication.

  - `monograph.source` (object)
    An extension object type #Reference.

  - `ingredient` (array)
    Identifies a particular constituent of interest in the product.

  - `ingredient.itemCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `ingredient.itemReference` (object)
    An extension object type #Reference.

  - `ingredient.isActive` (boolean)
    An extension object type #boolean.
    Example: true

  - `ingredient._isActive` (object)
    An extension object type #Element.

  - `ingredient.strength` (object)
    An extension object type #Ratio.

  - `preparationInstruction` (string)
    A string that may contain Github Flavored Markdown syntax for optional processing by a mark down presentation engine
    Example: "Sample markdown text"

  - `_preparationInstruction` (object)
    Base definition for all elements in a resource.

  - `intendedRoute` (array)
    The intended or approved route of administration.

  - `cost` (array)
    The price of the medication.

  - `cost.source` (string)
    An extension object type #string.
    Example: "example-string"

  - `cost.cost` (object, required)
    An extension object type #Money.

  - `monitoringProgram` (array)
    The program under which the medication is reviewed.

  - `monitoringProgram.name` (string)
    An extension object type #string.
    Example: "example-string"

  - `monitoringProgram._name` (object)
    An extension object type #Element.

  - `administrationGuidelines` (array)
    Guidelines for the administration of the medication.

  - `administrationGuidelines.dosage` (array)
    Dosage for the medication for the specific guidelines.

  - `administrationGuidelines.indicationCodeableConcept` (object)
    An extension object type #CodeableConcept.

  - `administrationGuidelines.indicationReference` (object)
    An extension object type #Reference.

  - `administrationGuidelines.patientCharacteristics` (array)
    Characteristics of the patient that are relevant to the administration guidelines (for example, height, weight, gender, etc.).

  - `medicineClassification` (array)
    Categorization of the medication within a formulary or classification system.

  - `medicineClassification.classification` (array)
    Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).

  - `packaging` (object)
    Information about a medication that is used to support knowledge.

  - `packaging.quantity` (object)
    An extension object type #Quantity.

  - `drugCharacteristic` (array)
    Specifies descriptive properties of the medicine, such as color, shape, imprints, etc.

  - `drugCharacteristic.valueString` (string)
    Description of the characteristic.
    Example: "example-string"

  - `drugCharacteristic.valueBase64Binary` (string)
    Description of the characteristic.
    Example: "U2FtcGxl"

  - `contraindication` (array)
    Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).

  - `regulatory` (array)
    Regulatory information about a medication.

  - `regulatory.regulatoryAuthority` (object, required)
    An extension object type #Reference.

  - `regulatory.substitution` (array)
    Specifies if changes are allowed when dispensing a medication from a regulatory perspective.

  - `regulatory.schedule` (array)
    Specifies the schedule of a medication in jurisdiction.

  - `regulatory.maxDispense` (object)
    An extension object type #MedicationKnowledge_MaxDispense.

  - `kinetics` (array)
    The time course of drug absorption, distribution, metabolism and excretion of a medication from the body.

  - `kinetics.areaUnderCurve` (array)
    The drug concentration measured at certain discrete points in time.

  - `kinetics.lethalDose50` (array)
    The median lethal dose of a drug.

  - `kinetics.halfLifePeriod` (object)
    An extension object type #Duration.

## Response 401 fields (application/json):

  - `message` (string, required)
    Error message indicating unauthorized access.
    Example: "Unauthorized"

  - `statusCode` (number, required)
    HTTP status code for unauthorized access.
    Example: 401


## Response 400 fields

## Response 404 fields